Daria Kurandina
UIC
The first visible light-induced Pd-catalyzed Heck reaction of a-heteroatom substituted alkyl iodides and bromides with vinyl arenes/heteroarenes has been developed. This transformation efficiently proceeds at room temperature and enables synthesis of valuable functionalized allylic systems, such as allylic silanes, -boronates, -germanes, -stannanes, -pivalates, -phosphonates, -phthalimides, and -tosylates from the corresponding a-substituted methyl iodides. Notably, synthesis of the latter substrates failed under existing thermally induced Pd-catalyzed conditions, which highlights the importance of visible light for this transformation.