54. “Unlocking Electrophilic N-Aryl Intermediates from Aryl Azides, Nitroarenes, and Aryl Amines in Cyclization-Migration Reactions” Driver, T. G. SynLett. 2022, in press, doi: 10.1055/a-1918-4191. link
53. “Recent Advances to Mediate Reductive Processes of Nitroarenes using Single Electron Transfer-, Organomagnesium-, or Organozinc Reagents.” Zhu, H.; Driver, T. G. Synthesis. 2022, 54, 3142-3161. doi: 10.1055/a-179206579. link
52. “Rh2(II)-Catalyzed Intermolecular N-Aryl Aziridination of Olefins using Nonactivated N-Atom Precursors.” Deng, T.; Mazumdar, W.; Yoshinaga, Y.; Patel, P. B.;✝ Malo, D.;✝ Malo, T.;✝ Wink, D. J.; Driver, T. G. J. Am. Chem. Soc. 2021, 143, 19149-19159. doi: 10.1021/jacs.1c09229. link
Preprint posted online May 23, 2021 on ChemRxiv.
✝undergraduate researcher
51. “Cu-Catalyzed Cross-Coupling of Nitroarenes with Aryl Boronic Acids to Construct Diarylamines.” Guan, X.; Zhu, H.; Driver, T. G. ACS Catal. 2021, 11, 12417-12422. doi: 10.1021/acscatal.1c03113. link
Preprint posted online July 5, 2021 on ChemRxiv.
50. "Nicotinamide Phosphoribosyltransferase Inhibitors and Methods for Use of the Same." Driver, T. G.; Machado, R.; Su, N.; Guan, X.; Mazumdar, W.; Ratia, K.; Hickok, J. R.; Lockett, A. D. US Patent Application No. 16/967,279; Pub. No: US 2021/007084 A1, published 3-11-2021.
49. “Counterion Control of tert-Butoxide-Mediated Single Electron Transfer to Nitrostilbenes Enables Access to N-Hydroxyindoles or Oxindoles.” Zhao, Y.; Zhu, H.; Sung, S; Wink, D. J.; Zadrozny, J. M.; Driver, T. G. Angew. Chem. Int. Ed. 2021, 60, 19207-19213. doi: 10.1002/anie.202104319.
48. “Recent Advances in the Development of Catalytic Methods that Construct Medium-ring Lactams. Partially Saturated Benzazepines and their Derivatives.” Mazumdar, W.; Driver, T. G. Synthesis, 2021, 53, 1734-1748. doi: 10.1055/s-0040-1705995. link
47. “I(III)-Catalyzed Oxidative Cyclization-Migration Tandem Reactions of Unactivated Anilines.” Deng, T.; Shi, E.;✝ Thomas, E.;✝ Driver, T. G. Org. Lett. 2020, 22, 9102-9106. doi: 10.1021/acs.orglett.0c03497. link
✝undergraduate researcher
46. “Oxidation of Non-Activated Anilines to Generate N-Aryl Nitrenoids.” Deng, T.; Mazumdar, W.; Ford, R. L.; Jana, N.; Izar, R.;✝ Wink, D. J.; Driver, T. G. J. Am. Chem. Soc. 2020, 142, 4456-4463. doi: 10.1021/jacs.9b13599. link
✝undergraduate researcher
45. “Development of a Carbon Neutral Pd-Catalyzed Reductive Cyclization of Nitroarenes.” Guan, X.; Zhu, H.; Zhao, Y.; Driver, T. G. Eur. J. Org. Chem. 2020, 57-60. link
44. “Intramolecular Pd-Catalyzed Reductive Amination of Enolizable sp3-C–H Bonds.” Ford, R.; Alt, I.; Jana, N.; Driver, T. G. Org. Lett. 2019, 21, 8827-8831. link
43. "Nicotinamide Phosphoribosyltransferase Inhibitors and Methods for Use of the Same." Driver, T. G.; Guan, X.; Mazumdar, W.; Su. N.; Ratia, K.; Hickok, J.; Lockett, A. D.; Machado, R. International Patent Application No. PCT/US2019/016684 filed 2-16-2019, published 8-8-2019.
42. “Controlling the Selectivity Patterns of Au-Catalyzed Cyclization–Migration Reactions” Chen, M.;✝ Su, N.; Deng, T.; Wink, D. J., Zhao, Y.; Driver, T. G. Org. Lett. 2019, 21, 1555-1558. link
✝undergraduate researcher
41. “Generation of Controllable Gaseous H2S Concentrations Using Microfluidics” Christoforidis, T.; Driver, T. G.; Rehman, J.; Eddington, D. T. RSC Adv. 2018, 8, 4078-4083. link
40. “An Inducer of Streptococcus Rgg2/3 Quorum Sensing Acts by Inhibiting Endopeptidase PepO” Pérez, T. G.; Ratia, K.; Wang, D.-S.; Driver, T. G.; Federle, M. J. Biol. Chem. 2018, 293, 931-940. link
39. “Iron-Catalyzed Reductive Cyclization of o-Nitrostyrenes using Phenylsilane as the Terminal Reductant” Shevlin, M.; Guan, X.; Driver, T. G. ACS Catal. 2017, 5518-5522. link
38. “Synthesis and Properties of New N-Heteroheptacenes for Solution-Based Organic Field Effect Transistors” Zhou, F.; Liu, S.; Santarsiero, B. D.; Wink, D. J.; Boudinet, D.; Facchetti, A.; Driver, T. G. Chem. Eur. J. 2017, 23, 12542-12549. link
37. “Achieving Site Selectivity in Metal-Catalyzed Electron-Rich Carbene Transfer Reactions from N-Tosylhydrazones.” Su, N.; Deng, T.; Wink, D. J.; Driver, T. G. Org. Lett. 2017, 19, 3990-3993. link
36. “Iron-Catalyzed Reductive Cyclization of o-Nitrostyrenes Using Phenylsilane as the Terminal Reductant.” Shevlin, M.; Guan, X.; Driver, T. G. ACS Catal. 2017, 5518-5522. link
35. “Rh2(II)-Catalyzed Ring Expansion of Cyclobutanol-Substituted Aryl Azides to Access Medium-Sized N-Heterocycles.” Mazumdar, W.; Jana, N.; Thurman, B. T.; Driver, T. G. J. Am. Chem. Soc. 2017, 139, 5031-5034. link
34. “Intermolecular Pd-Catalyzed Aryl C–H Bond Aminocarbonylation using Nitroarenes and Mo(CO)6.” Zhou, F.; Wang, D.-S.; Driver, T. G. Angew. Chem. Int. Ed. 2017, 56, 4530-4534. link
33. “Time-Gated Detection of Cystathionine γ-Lyase Activity with a Selective Luminogenic Hydrogen Sulfide Sensor.” Yao, Y.; Kong, C.; Lin, L.; Jain, A. D.; Thatcher, G. R.; Moore, T. W.; Driver, T. G. ; Miller, L. W. Chem. Eur. J. 2017, 23, 752-756. link
32. “Control of the Chemoselectivity of Metal N-Aryl Nitrene Reactivity: C–H Bond Amination versus Electrocyclization.” Jana, N.; Kong, C.; Jones, C.; Driver, T. G. J. Am. Chem. Soc. 2016, 138, 13271-13280. link
31. “Diborane-Mediated Deoxygenation of o-Nitrostyrenes to Form Indoles.” Yang, K.; Zhou, F.; Kuang, Z.; Gao, G.; Driver, T. G.; Song, Q. Org. Lett. 2016, 18, 4088-4091. link
30. “Mechanism of Rh2(II)-Catalyzed Indole Formation: The Catalyst Does Not Control Product Selectivity.” Harrison, J. G.; Gutierrez, O.; Jana, N.; Driver, T. G.; Tantillo, D. J. J. Am. Chem. Soc. 2016, 138, 487-490. link
29. “Pd-Catalyzed Formation of N-Heteroarenes using MoCO)6 as the Source of Carbon Monoxide.” Zhou, F.; Wang, D.-S.; Driver, T. G. Adv. Synth. Catal. 2015, 357, 3463-3468. link
28. “Copper-Catalyzed Formation of α-Alkoxycycloalkenones from N-Tosylhydrazones.” Su, N.; Theorell, J. A.;✝ Wink, Driver, T. G. Angew. Chem. Int. Ed. 2015, 54, 12942-12946. link
✝ = undergraduate researcher
27. “Assembly of Functionalized Carbocycles or N-Heterocycles Through a Domino Electrocyclization-[1,2] Migration Reaction Sequence.” Jana, N.; Driver, T. G. Org. Biomol. Chem. 2015, 13, 9720. link
26. “Promoting Reductive Tandem Reactions of Nitrostyrenes with Mo(CO)6 and a Palladium Catalyst to Produce 3H-Indoles.” Jana, N.; Zhou, F.; Driver, T. G. J. Am. Chem. Soc. 2015, 137, 6738. link
25. “Probing the Origin of Carboxylate Migration Selectivity in Rh2(II)-Catalyzed N-Heterocycle Formation from Trisubstituted Styryl Azides.” Kong, C.; Su, N.; Zhou, F.; Jana, N.; Driver, T. G. Tetrahedron. Lett. 2015, 56, 3262. Invited for symposium-in-print for Professor Harry Wasserman link
24. “Rh2(II)-Catalyzed Ester Migration to Afford 3H-Indoles from Trisubstituted Styryl Azides.” Kong, C.; Driver, T. G. Org. Lett. 2015, 17, 802. link
23. “Synthesis and Properties of Semiconducting Bispyrrolothiophenes for Organic Field Effect Transistors.” Jones, C.; Boudinet, D.; Xia, Y.; Denti, M.; Das, A.; Facchetti, A.; Driver, T. G. Chem. Eur. J. 2014, 20, 5938. link
22. “Efficient Synthesis of 3H-Indoles Enabled by the Lead-Mediated α-Arylation of β-Ketoesters or γ-Lactams using Aryl Azides.” Zhou, F.; Driver, T. G. Org. Lett. 2014, 16, 2916. link
21. “Development of Suzuki Cross-Coupling Reaction between 2-Azidoarylboronic Pinacolate Esters and Vinyl Triflates to Enable the Synthesis of [2,3]-Fused Indoles.” Jana, N.; Nguyen, Q.; Driver, T. G. J. Org. Chem. 2014, 79, 2781. link
20. “Rh2(II)-Catalyzed Formation of 1,2,3-Trisubstituted Indoles from Styryl Azides.” Jones, C.; Nguyen, Q.; Driver, T. G. Angew. Chem. Int. Ed. 2014, 53, 785. link
18. “Rh2(II)-Catalyzed Selective Aminomethylene Migration from Styryl Azides.” Kong, C.; Jana, N.; Driver, T. G. Org. Lett. 2013, 15, 824. link
17. “Iron(II) Bromide-Catalyzed Intramolecular C–H Bond Amination [1,2]-Shift Tandem Reactions of Aryl Azides.” Nguyen, Q.; Nguyen, T.;✝ Driver, T. G. J. Am. Chem. Soc. 2013, 135, 620. link
✝ = undergraduate researcher
16. “Ni-Catalyzed Alkenylation of Triazolopyridines: Synthesis of 2,6-Disubstituted Pyridines.” Liu, S.; Sawicki, J.;✝ Driver, T. G. Org. Lett. 2012, 14, 3744. link
15. “Rh2(II)-Catalyzed Intramolecular Aliphatic C–H Bond Amination Reactions using Aryl Azides as the N-Atom Source.” Nguyen, Q.; Sun, K.; Driver, T. G. J. Am. Chem. Soc. 2012, 134, 7262. link
14. “Rh2(II)-Catalyzed Synthesis of α-, β- or δ-Carbolines from Aryl Azides.” Pumphrey, A. L.; Dong, H.; Driver, T. G. Angew. Chem. Int. Ed. 2012, 51, 5920. link
13. “Transition Metal-Catalyzed Formation of N-Heterocycles via Aryl- or Vinyl C–H Bond Amination.” Stokes, B. J.; Driver, T. G. Eur. J. Org. Chem. 2011, 4071. link
12. “Ruthenium-Catalyzed γ-Carbolinium Ion Formation from Aryl Azides; Synthesis of Dimebolin.” Dong, H.; Latka, R. T.;✝ Driver, T. G. Org. Lett. 2011, 13, 2726. link
11. “Rh2(II)-Catalyzed Nitro-Group Migration Reactions: Selective Synthesis of 3-Nitroindoles from β-Nitro Styryl Azides.” Stokes, B. J.; Liu, S.; Driver, T. G. J. Am. Chem. Soc. 2011, 133, 4702. link
10. “Rhodium-Catalyzed Synthesis of 2,3-Disubstituted Indoles from β,β-Disubstituted Styryl Azides.” Sun, K.; Liu, S.; Bec, P. M.; ✝ Driver, T. G. Angew. Chem. Int. Ed. 2011, 50, 1702. link
Selected as a “hot” paper by the Editors
✝ = undergraduate researcher
9. “Recent Advances in Transition Metal-Catalyzed N-Atom Transfer Reactions of Azides.” Driver, T. G. Org. Biomol. Chem. 2010, 8, 3831. link
8. “Intramolecular Fe(II)-Catalyzed N–O or N–N Bond Formation from Aryl Azides.” Stokes, B. J.; Vogel, C. V.;✝ Urnezis, L. U.; Pan, M.; Driver, T. G. Org. Lett. 2010, 12, 2884. link
✝ = undergraduate researcher
7. "Examination of the Mechanism of Rh2(II)-Catalyzed Carbazole Formation Using Intramolecular Competition Experiments." Stokes, B. J.; Richert, K. J.;✝ Driver, T. G. J. Org. Chem. 2009, 74, 6442. link
✝ = undergraduate researcher
6. "Intramolecular Ir(I)-Catalyzed Benzylic C–H Bond Amination of ortho-Substituted Aryl Azides." Sun, K.; Sachwani, R.; Richert, K. J.;✝ Driver, T. G. Org. Lett. 2009, 11, 3598. link
✝ = undergraduate researcher
5. "Rh2(II)-Catalyzed Synthesis of Carbazoles from Biaryl Azides.” Stokes, B. J.; Jovanovic, B.;✝ Dong, H.; Richert, K. J.;✝ Riell, R. D.; Driver, T. G. J. Org. Chem. 2009, 74, 3225. link
✝ = undergraduate researcher
4. "Iron(II) Bromide-Catalyzed Synthesis of Benzimidazoles from Aryl Azides." Shen, M.; Driver, T. G. Org. Lett. 2008, 10, 3367. link
3. “Rh2(II)-Catalyzed Intramolecular C–H Amination of Aryl Azides.” Shen, M.; Leslie, B. E.; Driver, T. G. Angew. Chem. Int. Ed. 2008, 47, 5056. link
2. “Transition Metal-Mediated Synthesis of Pyrroles from Dienyl Azides.” Dong, H.; Shen, M.; Redford, J. E.;✝ Stokes, B. J.; Pumphrey, A. L.;✝ Driver, T. G. Org. Lett. 2007, 9, 5191. link
✝ = undergraduate researcher
1. “Intramolecular C–H Amination Reactions: Exploitation of the Rh2(II)-Catalyzed Decomposition of Azidoacrylates.” Stokes, B. J.; Dong, H.; Leslie, B. E.; Pumphrey, A. L.;✝ Driver, T. G. J. Am. Chem. Soc. 2007, 129, 7500. link
✝ = undergraduate researcher
Invited Publications
2. “C–H Bond Functionalization: An Aminated Reaction.” Driver, T. G. Nat. Chem. 2013, 5, 736. link
News and Views of a recent paper by Hennessy and Betley (Science 2013, 340, 591.)
1. “Niobium-Catalyzed Aryl CF3-Group Activation and C–H Bond Functionalization: An Efficient and Convergent Approach to the Synthesis of N-Heterocycles. Driver, T. G. Angew. Chem. Int. Ed. 2009, 48, 7974. link
Highlight of a recent paper by Akiyama and co-workers (Angew. Chem., Int. Ed. 2009, 48, 8070.)
Tom Driver's Supervised Career
